Vitamin D and Lung Infection

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Vitamin D serum level and chronic obstructive lung disease

Vitamin D serum level and chronic obstructive lung disease

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Vitamin D and lung disease.

The classic role of vitamin D in the regulation of calcium and phosphate metabolism, and its effects on bone health, are well established. More recently a critical role in immunity and respiratory health has been proposed. This arises from evidence for the capacity to generate the active metabolite, 1α,25-dihydroxyvitamin D3 (1,25(OH)D3), locally in many tissues beyond the kidney; expression of...

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Vitamin D and lung function.

Afzal et al recently reported that low plasma 25-hydroxyvitamin D is associated with a decline in lung function and chronic obstructive pulmonary disease (COPD). While this finding persisted after adjustment for possible confounding variables, and concurs with the findings of others, we believe it might still be spurious. First, we suggest the association between plasma vitamin D and lung funct...

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Maternal Vitamin D Status and Infant Infection

Maternal vitamin D status during pregnancy may modulate fetal immune system development and infant susceptibility to infections. Vitamin D deficiency is common during pregnancy, particularly among African American (AA) women. Our objective was to compare maternal vitamin D status (plasma 25(OH)D concentration) during pregnancy and first-year infections in the offspring of African American (AA) ...

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Vitamin D, bone, and HIV infection.

Vitamin D deficiency has been associated with increased risk for falls and fractures, diabetes and obesity, cardiovascular disease, some malignancies, and tuberculosis. Observational data have suggested benefit of higher vitamin D levels in many of these settings. However, data from randomized trials supporting the benefit of vitamin D supplementation are generally lacking, apart from data show...

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ژورنال

عنوان ژورنال: Infection and Immunity

سال: 2016

ISSN: 0019-9567,1098-5522

DOI: 10.1128/iai.00679-16